Kim Research Group
CRISPR Technology | Genetic Diversity | Protein Engineering
Department of Chemistry, York University, Canada
Hello, I’ve recently updated my name to Brian Kim. You can find my previous work using the names ‘Bill Kim’ or ‘Yongjoo Kim’, which I’ve noted in the Publications section. Thank you.
OUR RESEARCH
We engineer biological macromolecules (i.e., RNAs and proteins) that interact with nucleic acids. We use rational design and directed evolution to engineer new enzymes to create new forms of genetic diversity at the nucleotide, gene, and chromosomal levels.
These tools are used to enhance our understanding of proteins implicated in normal and pathogenic biological processes (functional genomics), as well as to discover new traits during protein evolution and crop breeding (biotechnology).
A secondary aim of our research is to understand general principles of protein & RNA design that optimizes their function in the intracellular milieu, in order to accelerate the development of macromolecular therapeutics with increased potency.
LATEST NEWS
